Smoking Is a Risk Factor for the Progression of Idiopathic Membranous Nephropathy
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چکیده
منابع مشابه
Smoking Is a Risk Factor for the Progression of Idiopathic Membranous Nephropathy
BACKGROUND Multiple studies have shown cigarette smoking to be a risk factor for chronic kidney disease. However, it is unknown whether smoking similarly increases the risk for progression of membranous nephropathy. METHODS This study used the Nagoya Nephrotic Syndrome Cohort Study (N-NSCS), including 171 patients with idiopathic membranous nephropathy (IMN) from 10 nephrology centers in Japa...
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BACKGROUND The adverse histological features predicting a progressive loss of renal function in idiopathic membranous nephropathy (IMN), before the establishment of impaired renal function with advanced glomerulosclerosis and/or interstitial fibrosis, are still poorly understood. The present study examined the relationship between the glomerular density (GD; non-sclerotic glomerular number/rena...
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Exciting progress recently has been made in our understanding of idiopathic membranous nephropathy, as well as treatment of this disease. Here, we review important advances regarding the pathogenesis of membranous nephropathy. We will also review the current approach to treatment and its limitations and will highlight new therapies that are currently being explored for this disease including Ri...
متن کاملIs dietary Acid a modifiable risk factor for nephropathy progression?
[11] , endothelin [10] , and aldosterone [10] . Together, these studies suggest that patients with reduced GFR but no metabolic acidosis nevertheless have acid retention that might mediate nephropathy progression. Reducing acid retention with less acid-producing diets that lower net endogenous acid production (NEAP) might slow nephropathy progression in patients with reduced GFR even without me...
متن کاملChapter 7: Idiopathic membranous nephropathy
BACKGROUND The diagnosis of MN is made on kidney biopsy. Diagnostic features include capillary wall thickening, normal cellularity, IgG and C3 along capillary walls on immunofluorescence, and subepithelial deposits on electron microscopy. MN is often seen in association with an underlying disorder (secondary MN). Secondary MN is more common in children (75%) than adults (25%) (Table 12). The di...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0100835